Mouse Speckle-type POZ protein (SPOP) ELISA Kit

SPOP encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.The SPOP gene encodes a 374-amino acid polypeptide that contains a poxvirus and zinc finger (POZ) domain and an evolutionarily conserved N-terminal region.

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SPECIFICATIONS

Catalog Number

KTE70240

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20747

Accession

Q6ZWS8

Additional Info

Mouse Speckle-type POZ protein (SPOP) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SPOP. No significant cross-reactivity or interference between Mouse SPOP and analogues was observed.