Mouse Sorbin and SH3 domain-containing protein 2 (SORBS2) ELISA Kit

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. SORBS2 encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

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SPECIFICATIONS

Catalog Number

KTE70409

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

234214

Accession

Q3UTJ2

Additional Info

Mouse Sorbin and SH3 domain-containing protein 2 (SORBS2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SORBS2. No significant cross-reactivity or interference between Mouse SORBS2 and analogues was observed.