SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes solute carrier family 2, facilitated glucose transporter member 4 that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in SLC2A4 have been associated with noninsulin-dependent diabetes mellitus (NIDDM).