Mouse Sodium-dependent dopamine transporter (SLC6A3) ELISA Kit

Dopamine transporterВ is a membrane-spanning protein that binds the neurotransmitter dopamine; DAT provides the primary mechanism through which dopamine is cleared from synapses, transporting dopamine from the synapse into a neuron. DAT is present in the peri-synaptic area of dopaminergic neurons in areas of the brain where dopamine signaling is common. DAT is implicated in a number of dopamine-related disorders, including attention deficit hyperactivity disorder, bipolar disorder, clinical depression, and alcoholism. DAT is located on human chromosome 5, consists of 15 coding exons, and is roughly 64 kbp long. Evidence for the associations between DAT and dopamine related disorders has come from a genetic polymorphism in the DAT, which influences the amount of protein expressed.

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SPECIFICATIONS

Catalog Number

KTE70420

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

13162

Accession

Q61327

Additional Info

Mouse Sodium-dependent dopamine transporter (SLC6A3) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SLC6A3. No significant cross-reactivity or interference between Mouse SLC6A3 and analogues was observed.