Mouse Signal transducer and activator of transcription 5B (STAT5B) ELISA Kit

Signal transducer and activator of transcription 5B is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.\nThis protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL).

Prices direct from Abbkine Scientific Co.Ltd.

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

KTE70267

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20851

Accession

P42232

Additional Info

Mouse Signal transducer and activator of transcription 5B (STAT5B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse STAT5B. No significant cross-reactivity or interference between Mouse STAT5B and analogues was observed.