Mouse Serine protease 33 (PRSS33) ELISA Kit

EOS contains 284 amino acids with an active form containing 248 amino acids starting from an Ile-Val-Gly-Gly motif. The active form comprises a catalytic triad of conserved amino acids: His77, Asp126 and Ser231. It shares 44% identity with beta-tryptase and belongs to the S1 trypsin-like serine-protease family. Interestingly, this gene also maps to human chromosome 16p13.3. Tissue distribution by immunohistochemistry analysis demonstrated that EOS is highly expressed in spleen and moderately expressed in intestine, colon, lung and brain. Since macrophages have important roles in various pathological conditions, such as wound healing, atherosclerosis and numerous inflammatory diseases, the localization of this novel serine protease to active macrophages may help to further the elucidation of the roles of this gene product in modulating these disorders.

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SPECIFICATIONS

Catalog Number

KTE70635

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

353130

Accession

Q80WM7

Additional Info

Mouse Serine protease 33 (PRSS33) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PRSS33. No significant cross-reactivity or interference between Mouse PRSS33 and analogues was observed.