Mouse Serine palmitoyltransferase 2 (SPTLC2) ELISA Kit

Serine palmitoyltransferase (SPT; EC 2.3.1.50) is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.\nSPTLC2encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the initial enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5'-phosphate dependent condensation of L-serine and palmitoyl CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.The LCB2 cDNA encodes a protein of 562 amino acids that is more than 90% identical to the mouse protein.

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SPECIFICATIONS

Catalog Number

KTE70251

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20773

Accession

P97363

Additional Info

Mouse Serine palmitoyltransferase 2 (SPTLC2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SPTLC2. No significant cross-reactivity or interference between Mouse SPTLC2 and analogues was observed.