Mouse Serglycin (SRGN) ELISA Kit

Serglycin is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.Serglycin plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2.

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SPECIFICATIONS

Catalog Number

KTE70254

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19073

Accession

P13609

Additional Info

Mouse Serglycin (SRGN) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SRGN. No significant cross-reactivity or interference between Mouse SRGN and analogues was observed.