Mouse Secretogranin-2 (SCG2) ELISA Kit

SCG2 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.SCG2 also has 9 potential dibasic cleavage sites, an N-glycosylation site not found in the bovine protein, and a putative sulfation site (tyr121). SCG2 was predicted to assume a secondary structure of alternating helix and turn structures over 45% and 40% of its length, respectively. The authors suggested that this structure may coordinate calcium.

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SPECIFICATIONS

Catalog Number

KTE70475

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20254

Accession

Q03517

Additional Info

Mouse Secretogranin-2 (SCG2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SCG2. No significant cross-reactivity or interference between Mouse SCG2 and analogues was observed.