Mouse Secreted phosphoprotein 24 (SPP2) ELISA Kit

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P.The deduced 399-amino acid protein has a calculated molecular mass of 44.7 kD and shares 39.3% amino acid identity with SGPP1. SGPP2 has an N-terminal hydrophobic region, 3 conserved phosphatase-family motifs, and is predicted to be an integral membrane protein with as many as 9 membrane-spanning segments. Immunofluorescence microscopy showed a reticular staining pattern in the perinuclear and cytosolic regions of HEK293 cells, and SGPP2 colocalized with an endoplasmic reticulum antibody. Northern blot analysis of human tissues detected a 5.1-kb transcript with high expression in kidney and heart, followed by brain, colon, lung, and small intestine.

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SPECIFICATIONS

Catalog Number

KTE70243

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

75396

Accession

Q8K1I3

Additional Info

Mouse Secreted phosphoprotein 24 (SPP2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SPP2. No significant cross-reactivity or interference between Mouse SPP2 and analogues was observed.