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Mouse S100 Calcium Binding Protein A8 (S100A8) ELISA Kit

Cat no: KTE70488

Mouse S100 Calcium Binding Protein A8 (S100A8) ELISA Kit

S100A8, a protein associated with a wide variety of inflammatory conditions, is heavily over-expressed in association with inflammation. Human S100A8 possesses neutrophil-repelling properties that result in an anti-inflammatory effect in vivo. The chemotactic activity of S100A8 on neutrophils was tested in Transwell chemotaxis assays. Analysis of the data indicates that S100A8 causes a repulsion of peripheral neutrophils, an activity that S100A8 loses upon its oxidation. S100A8 causes a strong anti-inflammatory effect in the rat air-pouch model of inflammation in vivo. These data highlight a naturally occurring novel anti-inflammatory pathway and provide potential molecular targets for the development of novel anti-inflammatory therapeutics.

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SPECIFICATIONS

Catalog Number

KTE70488

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20201

Accession

P27005

Additional Info

Mouse S100 Calcium Binding Protein A8 (S100A8) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse S100A8. No significant cross-reactivity or interference between Mouse S100A8 and analogues was observed.

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