Mouse Resistin-like beta (RETNLB) ELISA Kit

The 111-amino acid FIZZ2 protein, which shows 59% sequence identity to mouse Fizz2 and 47% identity to human FIZZ3, shares an N-terminal signal peptide and a C-terminal stretch of 10 cysteine residues with identical spacing with other FIZZ family members. Strong expression of mouse Fizz2 mRNA was found in the adult colon in the mucosal crypt epithelial cells. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.

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SPECIFICATIONS

Catalog Number

KTE70505

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

57263

Accession

Q99P86

Additional Info

Mouse Resistin-like beta (RETNLB) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse RETNLB. No significant cross-reactivity or interference between Mouse RETNLB and analogues was observed.