Mouse Protein phosphatase 1B (PPM1B) ELISA Kit

PPM1B is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.\nThe deduced 479-amino acid protein shows high sequence similarity to other mammalian PP2C-beta isoforms but has an extended and unique C-terminal portion.

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SPECIFICATIONS

Catalog Number

KTE70705

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19043

Accession

P36993

Additional Info

Mouse Protein phosphatase 1B (PPM1B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PPM1B. No significant cross-reactivity or interference between Mouse PPM1B and analogues was observed.