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Mouse Protein phosphatase 1 regulatory subunit 1B (PPP1R1B) ELISA Kit

Cat no: KTE70701

Mouse Protein phosphatase 1 regulatory subunit 1B (PPP1R1B) ELISA Kit

Midbrain dopaminergic neurons play a critical role in multiple brain functions, and abnormal signaling through dopaminergic pathways has been implicated in several major neurologic and psychiatric disorders.In the densely dopamine- and glutamate-innervated rat caudate-putamen, DARPP32 is expressed in medium-sized spiny neurons that also express dopamine D1 receptors. The function of DARPP32 seems to be regulated by receptor stimulation. Both dopaminergic and glutamatergic (NMDA) receptor stimulation regulate the extent of DARPP32 phosphorylation, but in opposite directions. Dopamine D1 receptor stimulation enhances cAMP formation, resulting in the phosphorylation of DARPP32; phosphorylated DARPP32 is a potent protein phosphatase-1.

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SPECIFICATIONS

Catalog Number

KTE70701

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19049

Accession

Q60829

Additional Info

Mouse Protein phosphatase 1 regulatory subunit 1B (PPP1R1B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PPP1R1B. No significant cross-reactivity or interference between Mouse PPP1R1B and analogues was observed.

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SUPPLIER INFO

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