Mouse Protein maelstrom homolog (MAEL) ELISA Kit

By excision of a P element insertion in the 5-prime UTR of the Drosophila maelstrom gene, Findley et al. (2003) isolated mael(M391), a allele of Drosophila maelstrom. They used database analysis to identify the human MAEL homolog. Confocal microscopy localized Drosophila maelstrom primarily to nuage, highly abundant particles within germline cells, and also to the nucleus and cytoplasm of germline cells. Nuclear shuttling assays showed that Drosophila maelstrom is transported between the cytoplasm and nucleus.By phenotypic characterization of Drosophila maelstrom mutants, which displayed axial patterning defects and other polarity defects, Findley et al. (2004) defined maelstrom as a spindle-class gene that affects Vasa modification.

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SPECIFICATIONS

Catalog Number

KTE71141

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

98558

Accession

Q8BVN9

Additional Info

Mouse Protein maelstrom homolog (MAEL) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MAEL. No significant cross-reactivity or interference between Mouse MAEL and analogues was observed.