Mouse Protein disulfide-isomerase (P4HB) ELISA Kit

PROHB is the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.

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SPECIFICATIONS

Catalog Number

KTE70794

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18453

Accession

P09103

Additional Info

Mouse Protein disulfide-isomerase (P4HB) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse P4HB. No significant cross-reactivity or interference between Mouse P4HB and analogues was observed.