Mouse Protein delta homolog 1 (DLK1) ELISA Kit

DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

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SPECIFICATIONS

Catalog Number

KTE71250

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

13386

Accession

Q09163

Additional Info

Mouse Protein delta homolog 1 (DLK1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse DLK1. No significant cross-reactivity or interference between Mouse DLK1 and analogues was observed.