Mouse Prolargin (PRELP) ELISA Kit

PREPL belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene.\nThe longest deduced protein contains 727 amino acids and has a propeller domain in its N-terminal half and a catalytic domain, including the catalytic triad (ser, asp, his) essential for serine peptidases, in its C-terminal half. In sharp contrast to PREP and oligopeptidase B, which require both amino- and carboxy-terminal sequences for activity, PREPL activity appeared to depend only on the carboxy-terminal domain.

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SPECIFICATIONS

Catalog Number

KTE70688

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

116847

Accession

Q9JK53

Additional Info

Mouse Prolargin (PRELP) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PRELP. No significant cross-reactivity or interference between Mouse PRELP and analogues was observed.