Mouse Polymerase I and transcript release factor (PTRF) ELISA Kit

PTRF encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts.\nThis protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression.

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SPECIFICATIONS

Catalog Number

KTE70609

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19285

Accession

O54724

Additional Info

Mouse Polymerase I and transcript release factor (PTRF) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PTRF. No significant cross-reactivity or interference between Mouse PTRF and analogues was observed.