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Mouse Phospholipase A-2-activating protein (PLAA) ELISA Kit

Cat no: KTE70736

Mouse Phospholipase A-2-activating protein (PLAA) ELISA Kit

Phospholipase A2-activating protein (PLAP) is potentially important in regulating the inflammatory response through its activation of phospholipase A2, which catalyzes the release of arachidonic acid. By screening a human monocyte cDNA library with a mouse Plap cDNA, Chopra et al. (1999) isolated human PLAP cDNAs. The 738-amino acid human PLAP protein predicted by the cDNA sequence has a molecular mass of 80,826 kD; however, immunoblot analysis using antibodies against PLAP detected a 72- to 74-kD protein in human monocyte cell lysates. In mouse macrophages, an antisense Plap oligonucleotide blocked cholera toxin-induced arachidonic acid release, indicating a role for PLAP in the regulation of phospholipase A2 activation.

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SPECIFICATIONS

Catalog Number

KTE70736

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18786

Accession

P27612

Additional Info

Mouse Phospholipase A-2-activating protein (PLAA) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PLAA. No significant cross-reactivity or interference between Mouse PLAA and analogues was observed.

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SUPPLIER INFO

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