Mouse Phosphoglycerate mutase 1 (PGAM1) ELISA Kit

Phosphoglyceric acid mutase is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The fact that the PGAMA and GOT1 loci are linked in the mouse supports the assignment of PGAMA to human chromosome 10. PGAM is a dimeric enzyme containing, in different tissues, different proportions of a muscle (MM) isozyme, a brain (BB) isozyme, and a hybrid form (MB). Electrophoresis of normal adult human muscle PGAM shows marked predominance of the MM band with only faint BB and MB bands. In most other human tissues, including brain, liver, erythrocytes, and leukocytes, PGAM-BB is the only demonstrable isozyme. In cardiac muscle extracts, all 3 bands are seen, although PGAM-MM predominates.

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SPECIFICATIONS

Catalog Number

KTE70768

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18648

Accession

Q9DBJ1

Additional Info

Mouse Phosphoglycerate mutase 1 (PGAM1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PGAM1. No significant cross-reactivity or interference between Mouse PGAM1 and analogues was observed.