Mouse Phosphatidylinositol-glycan biosynthesis class F protein (PIGF) ELISA Kit

PIGF encodes 1 of the enzymes involved in glycosylphosphatidylinositol (GPI) anchor biosynthesis. The primary biochemical defect in paroxysmal nocturnal hemoglobinuria (PNH), an acquired hematologic disorder with protean clinical manifestations including recurrent episodes of hemolysis, infections, and venous thrombosis, involves defective synthesis of GPI anchors that attach certain proteins to the cell surface membrane.\nProteins with appropriate C-terminal signal peptides are transferred to the preformed glycolipid anchor in the endoplasmic reticulum and transported to the cell surface as a single unit; in PNH, there is a defect in GPI-anchor biosynthesis and an absence of all surface proteins that use this anchoring motif.

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SPECIFICATIONS

Catalog Number

KTE70756

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18701

Accession

O09101

Additional Info

Mouse Phosphatidylinositol-glycan biosynthesis class F protein (PIGF) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PIGF. No significant cross-reactivity or interference between Mouse PIGF and analogues was observed.