Mouse Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2) ELISA Kit

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3-prime position. The products of these reactions serve as second messengers in growth signaling pathways. The kinase itself is made up of a catalytic subunit of molecular mass 110 kD (PIK3CA) and a regulatory subunit of either 85 kD, 55 kD, or 50 kD.\nBoth p85-alpha and p85-beta bound Xbp1s and increased its nuclear translocation, and it appeared that the p110 PI3K catalytic subunit and Xbp1s competed for binding of these regulatory subunits. p85-alpha and p85-beta formed an inactive dimer that was disrupted by insulin in a time-dependent manner, which promoted their association with Xbp1s.

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SPECIFICATIONS

Catalog Number

KTE70750

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18709

Accession

O08908

Additional Info

Mouse Phosphatidylinositol 3-kinase regulatory subunit beta (PIK3R2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PIK3R2. No significant cross-reactivity or interference between Mouse PIK3R2 and analogues was observed.