Mouse Periplakin (PPL) ELISA Kit

Periplakin is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.The deduced 1,666-amino acid protein has a calculated molecular mass of about 205 kD. PPL shares extensive sequence homology with other proteins of the plakin family, with highest identities found in the N- and C-terminal domains.

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SPECIFICATIONS

Catalog Number

KTE70706

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19041

Accession

Q9R269

Additional Info

Mouse Periplakin (PPL) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PPL. No significant cross-reactivity or interference between Mouse PPL and analogues was observed.