Mouse Patatin-like phospholipase domain-containing protein 2 (PNPLA2) ELISA Kit

The deduced 486-amino acid protein contains a highly conserved 180-amino acid N-terminal patatin domain with a glycine-rich region, an active serine hydrolase motif, and an aspartate active site motif. PNPLA2, which shows 88% amino acid homology to mouse desnutrin. Northern blot analysis detected a 2.0-kb transcript expressed at high levels in mouse brown and white adipose tissue and at intermediate levels in heart and testis. Very low expression was detected in all other mouse tissues examined. Expression of desnutrin was lower in gonadal fat deposits of genetically obese mice compared with wildtype mice. Desnutrin mRNA was found only in mature adipocytes and not in proliferating or confluent mouse preadipocytes. Expression was rapidly increased in cells induced to differentiate.

Prices direct from Abbkine Scientific Co.Ltd.

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

KTE70718

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

66853

Accession

Q8BJ56

Additional Info

Mouse Patatin-like phospholipase domain-containing protein 2 (PNPLA2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PNPLA2. No significant cross-reactivity or interference between Mouse PNPLA2 and analogues was observed.