Mouse Palmitoyl-protein thioesterase 1 (PPT1) ELISA Kit

PPT1 is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.\nThe cDNA predicted a 306-amino acid polypeptide that contains a 25-amino acid signal peptide, 3 N-linked glycosylation sites, and consensus motifs characteristic of thioesterases. Northern blot analysis revealed ubiquitous expression of a single 2.5-kb mRNA, with highest expression in lung, brain, and heart.

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SPECIFICATIONS

Catalog Number

KTE70698

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19063

Accession

O88531

Additional Info

Mouse Palmitoyl-protein thioesterase 1 (PPT1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PPT1. No significant cross-reactivity or interference between Mouse PPT1 and analogues was observed.