Mouse Nuclear receptor coactivator 2 (NCOA2) ELISA Kit

The nuclear receptor coactivator 2 encoded by Ncoa2 functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

KTE70803

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17978

Accession

Q61026

Additional Info

Mouse Nuclear receptor coactivator 2 (NCOA2) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse NCOA2. No significant cross-reactivity or interference between Mouse NCOA2 and analogues was observed.