Mouse Nuclear inhibitor of protein phosphatase 1 (PPP1R8) ELISA Kit

Nuclear inhibitor of protein phosphatase 1, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.The 351-amino acid NIPP1 protein is a specific inhibitor of type 1 serine/threonine protein phosphatases. The human ARD1 amino acid sequence is virtually identical to the carboxy terminus of the bovine NIPP1 amino acid sequence.

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SPECIFICATIONS

Catalog Number

KTE70700

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

100336

Accession

Q8R3G1

Additional Info

Mouse Nuclear inhibitor of protein phosphatase 1 (PPP1R8) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PPP1R8. No significant cross-reactivity or interference between Mouse PPP1R8 and analogues was observed.