Mouse Neural cell adhesion molecule L1 (L1CAM) ELISA Kit

L1, also known as L1CAM, is a transmembrane protein; it is a neuronal cell adhesion molecule, member of the L1 protein family, of 200-220 kDa, and involved in axon guidance and cell migration with a strong implication in treatment-resistant cancers. L1CAM has also been designated CD171 . The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin superfamily of proteins. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration, and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH.

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SPECIFICATIONS

Catalog Number

KTE71200

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Accession

P11627

Additional Info

Mouse Neural cell adhesion molecule L1 (L1CAM) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse L1CAM. No significant cross-reactivity or interference between Mouse L1CAM and analogues was observed.