Mouse Neurabin-2 (PPP1R9B) ELISA Kit

Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system.To identify proteins that interact with the ARF protein encoded by the CDKN2A gene, Vivo et al. (2001) used a yeast 2-hybrid screen of a human brain cDNA library with an ARF fusion construct as bait. By database searching with the identified clones, they reconstructed a full-length cDNA of human spinophilin. The deduced 813-amino acid protein shares 95% sequence identity with the rat homolog and contains an F-actin binding domain, a PP1C binding site, a PDZ domain, and a myosin-like left-handed alpha helix.

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SPECIFICATIONS

Catalog Number

KTE70699

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

217124

Accession

Q6R891

Additional Info

Mouse Neurabin-2 (PPP1R9B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PPP1R9B. No significant cross-reactivity or interference between Mouse PPP1R9B and analogues was observed.