Mouse Multidrug resistance-associated protein 1 (ABCC1) ELISA Kit

Multidrug resistance-associated protein 1 (MRP1) is a protein that in humans is encoded by the ABCC1 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.

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SPECIFICATIONS

Catalog Number

KTE70530

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17250

Accession

O35379

Additional Info

Mouse Multidrug resistance-associated protein 1 (ABCC1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse ABCC1. No significant cross-reactivity or interference between Mouse ABCC1 and analogues was observed.