Mouse Mediator of RNA polymerase II transcription subunit 1 (MED1) ELISA Kit

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by MED1 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.

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SPECIFICATIONS

Catalog Number

KTE71078

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

19014

Accession

Q925J9

Additional Info

Mouse Mediator of RNA polymerase II transcription subunit 1 (MED1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MED1. No significant cross-reactivity or interference between Mouse MED1 and analogues was observed.