logo
logo
Mouse Mediator of DNA damage checkpoint protein 1 (MDC1) ELISA Kit

Cat no: KTE71090

Mouse Mediator of DNA damage checkpoint protein 1 (MDC1) ELISA Kit

The protein encoded by Mdc1 contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 7 divergent copies of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. Mice with mutations in Mdc1 exhibit growth retardation, male infertility, immune defects, chromosome instability, DNA repair defects, and radiation sensitivity.

Prices direct from Abbkine Scientific Co.Ltd.

Quick response times

Exclusive Absave savings/discounts

SPECIFICATIONS

Catalog Number

KTE71090

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

240087

Accession

Q5PSV9

Additional Info

Mouse Mediator of DNA damage checkpoint protein 1 (MDC1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MDC1. No significant cross-reactivity or interference between Mouse MDC1 and analogues was observed.

Read more on Supplier website

SUPPLIER INFO

Latest promotions

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

Buy any polyclonal or monoclonal antibody from our extensive range of pre-made antibodies and for a limited time only receive a $50 discount!(T&C apply:...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...