Mouse Matrix metalloproteinase 13 (MMP-13) ELISA Kit

Mmp13 encodes a member of the matrix metalloproteinase family that plays a role in wound healing, skeletal development and bone remodeling. The encoded protein is activated by the removal of an N-terminal activation peptide to generate a zinc-dependent endopeptidase enzyme that can cleave various native collagens, including types I - IV, X and XIV. Mice lacking the encoded protein display profound defects in growth plate cartilage as well as a delay in the endochondral bone development. Lack of the encoded protein also impairs the wound healing process due to reduced keratinocyte migration and vascular density at the wound site. Mmp13 is located in a cluster of other matrix metalloproteinase genes on chromosome 9.

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SPECIFICATIONS

Catalog Number

KTE71010

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17386

Accession

P33435

Additional Info

Mouse Matrix metalloproteinase 13 (MMP-13) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MMP13. No significant cross-reactivity or interference between Mouse MMP13 and analogues was observed.