Mouse Mannan-binding lectin serine protease 1 (MASP1) ELISA Kit

Mannose-associated serine protease 1 (MASP1) is involved in the lectin pathway of the complement system and is responsible for cleaving C4 and C2 to form C4b2a, a C3-convertase.Mannose-binding lectin (MBL) is a serum component which participates in innate immunity by activating complement via a novel pathway. Human MBL forms complexes with two types of serine proteases termed MASP (MBL-associated serine protease).\nThese two proteases, MASP1 and MASP2, are structurally similar to one another as well as to C1r and C1s. Together, MASP, C1r and C1s constitute a novel serine protease family. It is likely that human MASP1 is able to activate C3, while human MASP2 cleaves C4, although further functional studies are required to confirm this.

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SPECIFICATIONS

Catalog Number

KTE71122

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17174

Accession

P98064

Additional Info

Mouse Mannan-binding lectin serine protease 1 (MASP1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MASP1. No significant cross-reactivity or interference between Mouse MASP1 and analogues was observed.