Mouse Malate Dehydrogenase (MDH) ELISA Kit

Mdh1 encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. Mdh1 encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. A pseudogene has been identified on chromosomes 12.

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SPECIFICATIONS

Catalog Number

KTE71086

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17449

Accession

P14152

Additional Info

Mouse Malate Dehydrogenase (MDH) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MDH1. No significant cross-reactivity or interference between Mouse MDH1 and analogues was observed.