Mouse Macrophage metalloelastase (MMP12) ELISA Kit

Mmp12 encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein have a diminished capacity to degrade extracellular matrix components, do not develop emphysema in response to long-term exposure to cigarette smoke, and exhibit impaired clearance and increased mortality upon bacterial infection. Mmp12 is located in a cluster of other matrix metalloproteinase genes on chromosome 9. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

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SPECIFICATIONS

Catalog Number

KTE71011

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17381

Accession

P34960

Additional Info

Mouse Macrophage metalloelastase (MMP12) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MMP12. No significant cross-reactivity or interference between Mouse MMP12 and analogues was observed.