Mouse Lysophosphatidic acid receptor 3 (LPAR3) ELISA Kit

LPA and the structurally related lysolipid mediator sphingosine 1-phosphate (S1P) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1) are S1P receptors; others (e.g., EDG2) are LPA receptors. EDG7 mediates responses to unsaturated LPA .Sequence analysis predicted that the 353-amino acid EDG7 protein shares approximately 54% and 49% amino acid identity with EDG2 and EDG4, respectively, and less than 40% identity with the S1P-specific receptors (e.g., EDG1). Northern blot analysis detected a 4.3-kb EDG7 transcript in heart, pancreas, prostate, and testis, with lower expression in lung, ovary, and some cancer cell lines. Western blot analysis showed that transfected cells express EDG7 as an approximately 35-kD protein.

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SPECIFICATIONS

Catalog Number

KTE71168

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

65086

Accession

Q9EQ31

Additional Info

Mouse Lysophosphatidic acid receptor 3 (LPAR3) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse LPAR3. No significant cross-reactivity or interference between Mouse LPAR3 and analogues was observed.