Mouse Lymphocyte antigen 75 (LY75) ELISA Kit

The LY75 protein has 77% overall amino acid identity with mouse Dec205. LY75 is a member of the MMR family of multidomain molecules. It contains a signal peptide, a cysteine-rich domain, a fibronectin type II domain, 10 carbohydrate recognition-like domains, a transmembrane domain, and a cytoplasmic tail. Northern blot analysis of hematopoietic cell lines revealed the presence of a predominant 7.8-kb and a secondary 9.5-kb transcript in myeloid, B-cell, and Hodgkin cell lines but not in the Jurkat T-cell line. In peripheral blood, immature DC contained barely detectable transcripts, which increased 50-fold upon differentiation and activation.LY75 acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment.

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SPECIFICATIONS

Catalog Number

KTE71148

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17076

Accession

Q60767

Additional Info

Mouse Lymphocyte antigen 75 (LY75) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse LY75. No significant cross-reactivity or interference between Mouse LY75 and analogues was observed.