Mouse Lupus La protein (SSB) ELISA Kit

Sjogren syndrome antigen B (autoantigen La), also known as SSB,La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus (SLE) (Teplova et al., 2006).Grolz and Bachmann (1997) stated that there are 3 La pseudogenes. They also found that alternative splicing gives rise to 3 different mRNAs, all of which were expressed in all tissues tested, and all of which were translated into nuclear La protein in transfected mouse cells.

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SPECIFICATIONS

Catalog Number

KTE70262

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20823

Accession

P32067

Additional Info

Mouse Lupus La protein (SSB) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SSB. No significant cross-reactivity or interference between Mouse SSB and analogues was observed.