Mouse Low-density lipoprotein receptor (LDLR) ELISA Kit

The Low-Density Lipoprotein (LDL) Receptor is a mosaic protein that mediates the endocytosis of cholesterol-rich LDL. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. The receptor also recognizes the apoE protein found in chylomicron remnants and VLDL remnants (IDL). Brown and Goldstein won a Nobel Prize for their identification of the Low Density Lipoprotein (LDL) receptor in 1985 whilst they were studying familial hypercholesterolemia.\nThe LDL receptor can be described as a chimeric protein. It is made up of a number of functionally distinct domains that can function independently of each other.

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SPECIFICATIONS

Catalog Number

KTE71192

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

16835

Accession

P35951

Additional Info

Mouse Low-density lipoprotein receptor (LDLR) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse LDLR. No significant cross-reactivity or interference between Mouse LDLR and analogues was observed.