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Mouse Histone lysine demethylase PHF8 (PHF8) ELISA Kit

Cat no: KTE70757

Mouse Histone lysine demethylase PHF8 (PHF8) ELISA Kit

PHF8 belongs to the family of ferrous iron and 2-oxoglutarate dependent oxygenases, and is active as a histone lysine demethylase with selectivity for the di-and monomethyl states.\nMutations in PHF8 cause Siderius type X-linked mental retardation (XLMR). In addition to moderate mental retardation, features of the Siderius-Hamel syndrome include facial dysmorphism, cleft lip and/or cleft palate, and in some cases microcephaly. A chromosomal microdeletion on Xp11.22 encompassing all of the PHF8 and FAM120C genes and a part of the WNK3 gene was reported in two brothers with autism spectrum disorder in addition to Siderius-type XLMR and cleft lip and palate.

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SPECIFICATIONS

Catalog Number

KTE70757

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

320595

Accession

Q80TJ7

Additional Info

Mouse Histone lysine demethylase PHF8 (PHF8) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PHF8. No significant cross-reactivity or interference between Mouse PHF8 and analogues was observed.

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