Mouse Histone deacetylase complex subunit SAP130 (SAP130) ELISA Kit

SF3B3 encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

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SPECIFICATIONS

Catalog Number

KTE70479

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

269003

Accession

Q8BIH0

Additional Info

Mouse Histone deacetylase complex subunit SAP130 (SAP130) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SAP130. No significant cross-reactivity or interference between Mouse SAP130 and analogues was observed.