Mouse Excitatory amino acid transporter 1 (SLC1A3) ELISA Kit

Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system. The cDNA encoded a deduced protein that was 95% homologous to a previously reported rabbit glutamate/aspartate transporter. The highest expression was found in the substantia nigra, red nucleus, and hippocampus, and in cerebral cortical layers

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SPECIFICATIONS

Catalog Number

KTE70431

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20512

Accession

P56564

Additional Info

Mouse Excitatory amino acid transporter 1 (SLC1A3) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SLC1A3. No significant cross-reactivity or interference between Mouse SLC1A3 and analogues was observed.