Mouse Doublesex- and mab-3-related transcription factor C1 (DMRTC1) ELISA Kit

DMRTC1 (DMRT-like family C1) is a 182 amino acid nuclear protein that exists as three alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC1 is expressed in Sertoli cells in male testis but, unlike other DMRT family members, it does not contain a DM DNA-binding domain. Highly expressed in ovary and testis. Detected in brain and in many other tissues. The gene encoding DMRTC1 maps to the human X chromosome, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited, including KlinefelterвЂ™s syndrome, TurnerвЂ™s syndrome, and Triple X syndrome.

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SPECIFICATIONS

Catalog Number

KTE71237

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

70887

Accession

Q9D9R7

Additional Info

Mouse Doublesex- and mab-3-related transcription factor C1 (DMRTC1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse DMRTC1. No significant cross-reactivity or interference between Mouse DMRTC1 and analogues was observed.