Mouse Double-strand break repair protein MRE11A (MRE11A) ELISA Kit

Mre11 encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

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SPECIFICATIONS

Catalog Number

KTE70953

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

17535

Accession

Q61216

Additional Info

Mouse Double-strand break repair protein MRE11A (MRE11A) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MRE11A. No significant cross-reactivity or interference between Mouse MRE11A and analogues was observed.