Mouse Disks large homolog 4 (DLG4) ELISA Kit

Disks large homolog 4 is a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. DLG4 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.

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SPECIFICATIONS

Catalog Number

KTE71256

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

13385

Accession

Q62108

Additional Info

Mouse Disks large homolog 4 (DLG4) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse DLG4. No significant cross-reactivity or interference between Mouse DLG4 and analogues was observed.