Mouse Cornifin-B (SPRR1B) ELISA Kit

All SPRR genes are closely linked within a 300-kb DNA segment on 1q21-q22.Marvin et al. (1992) characterized a cDNA clone corresponding to mRNA abundantly expressed in differentiating squamous cells originally isolated from a rabbit squamous cell library. Small Proline Rich Protein 1B is a 14-kD protein that appears to function as a component of the crosslinked envelope in squamous differentiating cells. Called cornifin, the protein has a high content of proline (31%), glutamine (20%), and cysteine (11%) and contains 13 repeats of an octapeptide (consensus sequence, EPCQPKVP) at its C terminus. In situ hybridization analysis showed that the mRNA is restricted to the suprabasal layers of the epidermis. Crosslinking of the protein appears to be mediated by transglutaminase type I.

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SPECIFICATIONS

Catalog Number

KTE70247

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

20754

Accession

Q62267

Additional Info

Mouse Cornifin-B (SPRR1B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse SPRR1B. No significant cross-reactivity or interference between Mouse SPRR1B and analogues was observed.