Mouse CAMP-dependent protein kinase catalytic subunit beta (PRKACB) ELISA Kit

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the AMP-activated protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans.\nPRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.

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SPECIFICATIONS

Catalog Number

KTE70673

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18749

Accession

P68181

Additional Info

Mouse CAMP-dependent protein kinase catalytic subunit beta (PRKACB) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PRKACB. No significant cross-reactivity or interference between Mouse PRKACB and analogues was observed.