Mouse Calcium-dependent phospholipase A2 (PLA2G5) ELISA Kit

PLA2G5 is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L-alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol.

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SPECIFICATIONS

Catalog Number

KTE70739

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

18784

Accession

P97391

Additional Info

Mouse Calcium-dependent phospholipase A2 (PLA2G5) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse PLA2G5. No significant cross-reactivity or interference between Mouse PLA2G5 and analogues was observed.